Preheat oven to 400°F (200°C). Line a baking sheet with parchment paper.
In a large mixing bowl, whisk together flour, sugar, baking powder, and salt.
Cut in the cold, cubed butter using a pastry cutter until the mixture resembles coarse crumbs.
Gently fold in the blueberries.
In a separate bowl, mix together the heavy cream and vanilla extract. Pour over the dry ingredients and stir until just combined.
Turn the dough out onto a floured surface and shape into a circle about 1 inch thick. Cut into 8 wedges and place on the prepared baking sheet.
Bake for 18-20 minutes, or until golden brown. Let cool on a wire rack.
For the glaze, whisk together the powdered sugar and lemon juice until smooth. Drizzle over the cooled scones.